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PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth.

Gao T, Furnari F, Newton AC
Mol Cell. 2005 Apr 1. 18(1):13-24. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
22404pcDNA3-HA-PHLPP1 N-terminal truncationExpresses a HA tagged, N-terminal truncation of human PHLPP1 in mammalian cells
22930pcDNA3-HA-PHLPP1(N-terminal truncation)-deltaPHMammalian expression of a HA tagged, N-terminal truncation of human PHLPP1 containing a deletion of the PH domain
22931pcDNA3-HA-PHLPP1(N-terminal truncation)-deltaCMammalian expression of a HA tagged, N-terminal truncation of human PHLPP1 containing a deletion of the PDZ binding motif (delta C)

Antibodies from Article