PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth.
Gao T, Furnari F, Newton AC
Mol Cell. 2005 Apr 1. 18(1):13-24.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
22404 | pcDNA3-HA-PHLPP1 N-terminal truncation | Expresses a HA tagged, N-terminal truncation of human PHLPP1 in mammalian cells |
22930 | pcDNA3-HA-PHLPP1(N-terminal truncation)-deltaPH | Mammalian expression of a HA tagged, N-terminal truncation of human PHLPP1 containing a deletion of the PH domain |
22931 | pcDNA3-HA-PHLPP1(N-terminal truncation)-deltaC | Mammalian expression of a HA tagged, N-terminal truncation of human PHLPP1 containing a deletion of the PDZ binding motif (delta C) |