Cingulin binds to the ZU5 domain of scaffolding protein ZO-1 to promote its extended conformation, stabilization, and tight junction accumulation.
Vasileva E, Spadaro D, Rouaud F, King JM, Flinois A, Shah J, Sluysmans S, Mean I, Jond L, Turner JR, Citi S
J Biol Chem. 2022 Apr;298(4):101797. doi: 10.1016/j.jbc.2022.101797. Epub 2022 Mar 5.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 236507 | GFP-hCGN | For expression of hCingulin in mammalian cells |
| 236508 | hCGN-HA | For expression of hCingulin in mammalian cells |
| 236509 | GFP-mCGN-Myc | For expression of mCingulin in mammalian cells |
| 236510 | mCGN-Myc-His | For expression of mCingulin in mammalian cells |
| 236514 | GFP-mCGNL1-Myc | For expression of mParacingulin L1 in mammalian cells |
| 236515 | hCGNL1-Myc-HA | For expression of hParacingulinL1 in mammalian cells |