RAD52 resolves transcription-replication conflicts to mitigate R-loop induced genome instability.
Jalan M, Sharma A, Pei X, Weinhold N, Buechelmaier ES, Zhu Y, Ahmed-Seghir S, Ratnakumar A, Di Bona M, McDermott N, Gomez-Aguilar J, Anderson KS, Ng CKY, Selenica P, Bakhoum SF, Reis-Filho JS, Riaz N, Powell SN
Nat Commun. 2024 Sep 5;15(1):7776. doi: 10.1038/s41467-024-51784-x.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 235676 | pcDNA3.1-HA-RAD52-WT | Expresses HA-tagged wild type human RAD52 in mammalian cells. |
| 235677 | pcDNA3.1-HA-RAD52-∆C | Expresses HA-tagged mutant human RAD52 in mammalian cells with a C-terminal deletion (Δ302-410 amino acids). |
| 235678 | pcDNA3.1-HA | Plasmid control for pcDNA3.1-HA-RAD52-WT and pcDNA3.1-HA-RAD52-∆C |