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Engineered CRISPR-Cas9 for Streptomyces sp. genome editing to improve specialized metabolite production.

Kim DG, Gu B, Cha Y, Ha J, Lee Y, Kim G, Cho BK, Oh MK
Nat Commun. 2025 Jan 21;16(1):874. doi: 10.1038/s41467-025-56278-y. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
234428pCRISPomyces-2BDPlasmid for Streptomyces containing gene of modified Cas9-BD protein and sequence of sgRNA cloning template
234429pdCRISPomyces-2BDPlasmid for Streptomyces containing gene of modified dCas9-BD protein and sequence of sgRNA cloning template

Antibodies from Article