Two distinct long-range synaptic complexes promote different aspects of end processing prior to repair of DNA breaks by non-homologous end joining.
Buehl CJ, Goff NJ, Hardwick SW, Gellert M, Blundell TL, Yang W, Chaplin AK, Meek K
Mol Cell. 2023 Mar 2;83(5):698-714.e4. doi: 10.1016/j.molcel.2023.01.012. Epub 2023 Jan 31.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 233911 | RMCE wild type DNA-PKcs | Low copy number provides expression of human DNA-PKcs |
| 233914 | RMCE ABCDE>ala DNA-PKcs | Low copy number provides expression of human DNA-PKcs with the 6 ABCDE phosphorylation sites substituted to alanine. |