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Sefi Rosenbluh Lab: SRP19 and the protein secretion machinery is a targetable vulnerability in cancers with APC loss

Xi X, Liu L, Tuano N, Tailhades J, Mouradov D, Sieber O, Cryle M, Segelov E, Rosenbluh J
bioRxiv 2024.01.30.578083; doi: https://doi.org/10.1101/2024.01.30.578083

Plasmids from Article

ID Plasmid Purpose
233289inducible shSRP19_9 in pLKO tet onDox inducible expression of SRP19 shRNA
233290SEAP (Protein secretion reporter) in pLX317SEAP reporter (used for monitoring protein secretion)
233291SRP19 (siRNA resistant) in pLX311Expression of WT SRP19 (siRNA resistant)
233292SRP19 in pLX311Expression of WT SRP19

Antibodies from Article