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Engineering inducible signaling receptors to enable erythropoietin-free erythropoiesis

Shah AP, Majeti KR, Ekman FK, Selvaraj S, Soupene E, Chati P, Sinha R, Luna SE, Charlesworth CT, McCreary T, Lesch BJ, Tran T, Sharma D, Chu SN, Porteus MH, Cromer MK
bioRxiv 2024.04.12.589260 (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
232414MKC176_EPOR(2A-synEPOR)AAV production plasmid for EPOR(synEPOR) vector from Figs. 3-5 that mediates HDR at EPOR locus using EPOR gRNA. synEPOR is codon diverged to prevent premature recombination with EPOR locus.

Antibodies from Article