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Interleukin-1alpha release during necrotic-like cell death generates myeloid-driven immunosuppression that restricts anti-tumor immunity.

Hanggi K, Li J, Gangadharan A, Liu X, Celias DP, Osunmakinde O, Keske A, Davis J, Ahmad F, Giron A, Anadon CM, Gardner A, DeNardo DG, Shaw TI, Beg AA, Yu X, Ruffell B
Cancer Cell. 2024 Nov 13:S1535-6108(24)00402-1. doi: 10.1016/j.ccell.2024.10.014. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
231985pHIV-EF1a-2A-ZsGreenEmpty backbone for expression of GoI with Bi-cistronic expression ZsGreen
231987pHIV-EF1a-Il1a-ZsGreenExpress IL-1alpha-ZsGreen fusion protein

Antibodies from Article