IFN-gamma licenses normal and pathogenic ALPK1/TIFA pathway in human monocytes.
Martin A, Caron S, Marcotte M, Bronnec P, Garneret E, Martel N, Maalouf G, Seve P, Saadoun D, Jamilloux Y, Henry T
iScience. 2024 Dec 10;28(1):111563. doi: 10.1016/j.isci.2024.111563. eCollection 2025 Jan 17.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 231585 | pInducer20 ALPK1 WT | ALPK1 WT gene under control of a doxycycline-inducible promoter |
| 231586 | pInducer20 ALPK1 T237M | ALPK1 gene mutated in position T237M (Pathogenic mutation in ROSAH syndrome) under control of a doxycycline-inducible promoter |
| 231587 | pInducer20 ALPK1 Y254C | ALPK1 gene mutated in position Y254C (Pathogenic mutation in ROSAH syndrome) under control of a doxycycline-inducible promoter |
| 231588 | pInducer20 ALPK1 V1092A | ALPK1 gene mutated in position V1092A (mutation found in spiradenomacarcinoma (sweat gland cancer)) under control of a doxycycline-inducible promoter |
| 231589 | pInducer20 TIFA WT | TIFA WT gene under control of a doxycycline-inducible promoter |
| 231590 | pInducer20 TIFA T9A | TIFA gene mutated in position T9A (mutation on phosphorylation site) under control of a doxycycline-inducible promoter |