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A modular toolbox for the optogenetic deactivation of transcription.

Muench P, Fiumara M, Southern N, Coda D, Aschenbrenner S, Correia B, Graff J, Niopek D, Mathony J
Nucleic Acids Res. 2024 Dec 16:gkae1237. doi: 10.1093/nar/gkae1237. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
231566dCas9-AsLOV2x3-NLSx3Expresses components of the LOOMINA optogenetic transcriptional control system.
231567CMV_dCas9-AsLOV2x3-NLSx3Expresses components of the LOOMINA optogenetic transcriptional control system.
231568CMV_Zdk3-VPR_P2A_dCas9-AsLOVx3-NLSx3Expresses components of the LOOMINA optogenetic transcriptional control system.
231569cpLOV2-Gal4Expresses components of the LOOMINA optogenetic transcriptional control system.
231571Zdk3-VP64Expresses components of the LOOMINA optogenetic transcriptional control system.
231573CMV_Zdk3-VPRExpresses components of the LOOMINA optogenetic transcriptional control system.

Antibodies from Article