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New MiniPromoter Ple389 (ADORA2A) drives selective expression in medium spiny neurons in mice and non-human primates.

de Moura Gomes A, L Petkau T, J Korecki A, Fornes O, Galvan A, Lu G, M Hill A, Ling Lam S, Yao A, A Farkas R, W Wasserman W, Smith Y, M Simpson E, R Leavitt B
Sci Rep. 2024 Nov 15;14(1):28194. doi: 10.1038/s41598-024-79004-y. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
158098pEMS2075High Copy number plasmid containing smCBA insert.
158099pEMS2156High Copy number plasmid containing SYN1 insert
225630pEMS2372High Copy number plasmid containing Ple389 (ADORA2A MiniPromoter) insert
225631pEMS2374High Copy number plasmid containing Ple391 (DRD2 MiniPromoter) insert
225632pEMS2368High Copy number plasmid containing Ple385 (GPR6 MiniPromoter) insert
225633pEMS2387AAV plasmid with Ple389 (ADORA2A MiniPromoter) driving expression of EmGFP. Contains WPRE.
225634pEMS2389AAV plasmid with Ple391 (DRD2 MiniPromoter) driving expression of EmGFP. Contains WPRE.
225635pEMS2383AAV plasmid with Ple385 (GPR6 MiniPromoter) driving expression of EmGFP. Contains WPRE.

Antibodies from Article