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Transsulfuration pathway activation attenuates oxidative stress and ferroptosis in sickle primary erythroblasts and transgenic mice.

Xi C, Pang J, Xue W, Cui Y, Jiang N, Zhi W, Shi H, Horuzsko A, Pace BS, Zhu X
Commun Biol. 2025 Jan 6;8(1):15. doi: 10.1038/s42003-024-07424-7. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
230080pLentiCRISPR v2-sgControlCrispr knock out control
230081pLentiCRISPR v2-sgCBS-1Crispr knock out human CBS gene
230082pLentiCRISPR v2-sgCBS-2Crispr knock out human CBS gene
230083pLentiCRISPR v2-sgL2HGDH-1Crispr knock out human L2HGDH gene
230084pLentiCRISPR v2-sgL2HGDH-2Crispr knock out human L2HGDH gene
230085pLentiCRISPR v2-sgL2HGDH-3Crispr knock out human L2HGDH gene
230086pLKO.1_puro_shNRF2-1shRNA silencing human NRF2 gene
230087pLKO.1_puro_shNRF2-2shRNA silencing human NRF2 gene

Antibodies from Article