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LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons

Baptiste Libé-Philippot, Amélie Lejeune, Keimpe Wierda, Nikolaos Louros, Emir Erkol, Ine Vlaeminck, Sofie Beckers, Vaiva Gaspariunaite, Angéline Bilheu, Katerina Konstantoulea, Hajnalka Nyitrai, Matthias De Vleeschouwer, Kristel M Vennekens, Niels Vidal, Thomas W Bird, Daniela C Soto, Tom Jaspers, Maarten Dewilde, Megan Y Dennis, Frederic Rousseau, Davide Comoletti, Joost Schymkowitz, Tom Theys, Joris de Wit, Pierre Vanderhaeghen
Cell. 2023 Dec 21;186(26):5766-5783.e25. doi: 10.1016/j.cell.2023.11.028. (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
220790pCIG-LRRC37BTo express the human receptor LRRC37B in mammalian cells together with EGFP
220791pCIG-LSL-LRRC37BTo express the human receptor LRRC37B (cre-dependant) in mammalian cells together with EGFP
220792pCIG-LRRC37B-HATo express the human receptor LRRC37B HA-tagged in mammalian cells together with EGFP
220793pCIG-FGF13ATo express the human FGF13 isoform 1(FGF13A) in mammalian cells together with EGFP
220794pCIG-LRRC37Bchimpanzee-HATo express the chimpanzee receptor LRRC37B in mammalian cells together with EGFP

Antibodies from Article