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LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons.

Libe-Philippot B, Lejeune A, Wierda K, Louros N, Erkol E, Vlaeminck I, Beckers S, Gaspariunaite V, Bilheu A, Konstantoulea K, Nyitrai H, De Vleeschouwer M, Vennekens KM, Vidal N, Bird TW, Soto DC, Jaspers T, Dewilde M, Dennis MY, Rousseau F, Comoletti D, Schymkowitz J, Theys T, de Wit J, Vanderhaeghen P
Cell. 2023 Dec 21;186(26):5766-5783.e25. doi: 10.1016/j.cell.2023.11.028. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
220790pCIG-LRRC37BTo express the human receptor LRRC37B in mammalian cells together with EGFP
220791pCIG-LSL-LRRC37BTo express the human receptor LRRC37B (cre-dependant) in mammalian cells together with EGFP
220792pCIG-LRRC37B-HATo express the human receptor LRRC37B HA-tagged in mammalian cells together with EGFP
220793pCIG-FGF13ATo express the human FGF13 isoform 1(FGF13A) in mammalian cells together with EGFP
220794pCIG-LRRC37Bchimpanzee-HATo express the chimpanzee receptor LRRC37B in mammalian cells together with EGFP

Antibodies from Article