MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer.
Klingbeil O, Skopelitis D, Tonelli C, Yoshimoto T, Alpsoy A, Panepinto MC, Minicozzi F, Merrill JR, Cafiero AM, Aggarwal D, Russo S, Ha T, Demerdash OE, Wee TL, Spector DL, Lyons SK, Tuveson DA, Cifani P, Vakoc CR
Cancer Discov. 2024 Jul 26. doi: 10.1158/2159-8290.CD-23-1529.
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 229396 | HA-MAP4K1 | Lentiviral or overpexression of cDNA |
| 229400 | HA-MAP4K5 | Lentiviral or overpexression of cDNA |
| 229402 | HA-MAP4K7 | Lentiviral or overpexression of cDNA |
| 229403 | HA-MAP4K4-10A | Lentiviral or overpexression of cDNA |
| 229404 | HA-MAP4K4-10D | Lentiviral or overpexression of cDNA |
| 229405 | FLAG-MKI-P2A-GFP | Lentiviral or overpexression of cDNA |
| 229406 | FLAG-MKI-MUT-P2A-GFP | Lentiviral or overpexression of cDNA |
| 229407 | FLAG-MKI-P2A-GFP-DOX-N | Lentiviral or overpexression of cDNA |
| 229408 | FLAG-MKI-MUT-P2A-GFP-DOX-N | Lentiviral or overpexression of cDNA |
| 229410 | HA-CDC25C | Lentiviral or overpexression of cDNA |
| 229411 | HA-TEAD1 | Lentiviral or overpexression of cDNA |
| 229412 | HA-YAP-wt | Lentiviral or overpexression of cDNA |
| 229413 | HA-YAP-5A | Lentiviral or overpexression of cDNA |
| 229414 | HA-TAZ-4A | Lentiviral or overpexression of cDNA |
| 229415 | HA-YAP-5D | Lentiviral or overpexression of cDNA |
| 229416 | HA-TAZ-4D | Lentiviral or overpexression of cDNA |
| 229417 | HA-MST1 | Lentiviral or overpexression of cDNA |
| 229420 | HA-MST2-S444A | Lentiviral or overpexression of cDNA |
| 229422 | FLAG-MARK3-CR | Lentiviral or overpexression of cDNA |
| 229423 | FLAG-MARK2-GK-CR | Lentiviral or overpexression of cDNA |
| 229424 | FLAG-MARK3-GK-CR | Lentiviral or overpexression of cDNA |
| 229425 | FLAG-MARK2-K82H-CR | Lentiviral or overpexression of cDNA |
| 229426 | V5-14-3-3-e | Lentiviral or overpexression of cDNA |
| 229427 | HA-MOB1A | Lentiviral or overpexression of cDNA |
| 229428 | HA-MOB1B | Lentiviral or overpexression of cDNA |
| 229429 | sgMST1/2-1 | knockout of MST1 and MST2 |
| 229430 | sgMST1/2-2 | knockout of MST1 and MST2 |
| 229431 | sgLATS1/2-1 | knockout of LATS1 and LATS2 |
| 229432 | sgLATS1/2-2 | knockout of LATS1 and LATS2 |
| 229434 | sgMARK2-R-1 | knockout of MARK2 |
| 229435 | sgMARK2-R-2 | knockout of MARK2 |
| 229436 | sgMARK2-R-3 | knockout of MARK2 |
| 229437 | sgMARK3-R-1 | knockout of MARK3 |
| 229439 | sgMARK3-R-3 | knockout of MARK3 |
| 229440 | sgMARK2-3-1 | knockout of MARK2 and MARK3 |
| 229441 | sgMARK2-3-2 | knockout of MARK2 and MARK3 |
| 229442 | sgMARK2-3-3 | knockout of MARK2 and MARK3 |
| 229443 | sgCDK1-ROSA | knockout of CDK1 |
| 229448 | sgTAZ-R-1 | knockout of WWTR1 (TAZ) |
| 229449 | sgTAZ-R-2 | knockout of WWTR1 (TAZ) |
| 229450 | sgTAZ-R-3 | knockout of WWTR1 (TAZ) |
| 229453 | sgYAP-TAZ-3 | knockout of YAP1 and WWTR1 (TAZ) |