Mechanism-guided engineering of a minimal biological particle for genome editing
W. Ngo, J. Peukes, A. Baldwin, Z.W. Xue, S. Hwang, R.R. Stickels, Z. Lin, A.T. Satpathy, J.A. Wells, R. Schekman, E. Nogales, J.A. Doudna
Proc. Natl. Acad. Sci. U.S.A., 122 (1), e2413519121, 2025
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 228957 | pWN_U6-B2M-miniGag | miniEDV production plasmid. Expresses the miniGag (CAG promoter) and sgRNA (human U6 promoter) |
| 228958 | pWN_U6-B2M-miniGag-Cas9 | miniEDV production plasmid. Expresses the miniGag-Cas9 polypeptide (CAG promoter) and sgRNA (human U6 promoter) |
| 228959 | pWN_U6-TRAC-miniGag-Cas9 | miniEDV production plasmid. Expresses the miniGag-Cas9 polypeptide (CAG promoter) and sgRNA (human U6 promoter) |
| 228960 | pWN_U6-TRAC-miniGag | miniEDV production plasmid. Expresses the miniGag polypeptide (CAG promoter) and sgRNA (human U6 promoter) |