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TMEM16 and OSCA/TMEM63 proteins share a conserved potential to permeate ions and phospholipids.

Lowry AJ, Liang P, Song M, Serena Wan YC, Pei ZM, Yang H, Zhang Y
bioRxiv [Preprint]. 2024 Sep 3:2024.02.04.578431. doi: 10.1101/2024.02.04.578431. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
228577TMEM16F-I521A-peGFP-N1Expresses mouse TMEM16F-I521A-eGFP in mammalian cells
228578TMEM16F-I521E-peGFP-N1Expresses mouse TMEM16F-I521E-eGFP in mammalian cells
228579TMEM16F-M522K-peGFP-N1Expresses mouse TMEM16F-M522K-eGFP in mammalian cells
228580TMEM16F-T526K-peGFP-N1Expresses mouse TMEM16F-T526K-eGFP in mammalian cells
228581TMEM16F-I611K-peGFP-N1Expresses mouse TMEM16F-I611K-eGFP in mammalian cells
228582TMEM16A-I546K-peGFP-N1Expresses mouse TMEM16A-I546K-eGFP in mammalian cells
228583TMEM16A-I547K-peGFP-N1Expresses mouse TMEM16A-I547K-eGFP in mammalian cells
228584TMEM16A-E551K-peGFP-N1Expresses mouse TMEM16A-E551K-eGFP in mammalian cells
228585OSCA1.2-peGFP-N1Expresses OSCA1.2-eGFP in mammalian cells
228586OSCA1.2-K435L-peGFP-N1Expresses OSCA1.2-K435L-eGFP in mammalian cells
228587OSCA1.2-K435L-L438K-peGFP-N1Expresses OSCA1.2-K435L-L438K-eGFP in mammalian cells
228588TMEM16F-I521K-peGFP-N1Expresses TMEM16F-I521K-peGFP in mammalian cells
228589OSCA1.2-A439K-peGFP-N1Expresses OSCA1.2-A439K-eGFP in mammalian cells
228590TMEM63A-peGFP-N1Expresses mouse TMEM63A-eGFP in mammalian cells
228591TMEM63A-W472K-peGFP-N1Expresses mouse TMEM63A-W472K-eGFP in mammalian cells
228592TMEM63A-S475K-peGFP-N1Expresses mouse TMEM63A-S475K-eGFP in mammalian cells
228593TMEM63A-A476K-peGFP-N1Expresses mouse TMEM63A-A476K-eGFP in mammalian cells

Antibodies from Article