Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity.
Fontana P, Du G, Zhang Y, Zhang H, Vora SM, Hu JJ, Shi M, Tufan AB, Healy LB, Xia S, Lee DJ, Li Z, Baldominos P, Ru H, Luo HR, Agudo J, Lieberman J, Wu H
Cell. 2024 Sep 2:S0092-8674(24)00898-5. doi: 10.1016/j.cell.2024.08.007.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 228254 | pLenti-CMV-GSDMD-eGFP-SV40p-BlasR | pLenti-CMV-GSDMD-eGFP-SV40p-BlasR plasmid for ectopic expression of human full-length GSDMD fusion with GFP |
| 228271 | pLenti-CMV-eGFP-SV40p-BlasR | pLenti-CMV-eGFP-SV40p-BlasR plasmid for ectopic expression of GFP |