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Rapid discovery of cyclic peptide protein aggregation inhibitors by continuous selection.

Yang L, Zhang J, Andon JS, Li L, Wang T
Nat Chem Biol. 2025 Jan 13. doi: 10.1038/s41589-024-01823-x. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
227929pLY009Express Aβ42-T7n
227930pTW357bLow-stringency accessory plasmid for selection
227931pTW357d5High-stringency accessory plasmid for selection
227932pTW357bNAccessory plasmid for negative selection
227933pTW358bExpress Aβ42-T7n
227934pTW358cExpress Aβ42 F19S/L34P-T7n
227935pTW358fExpress hIAPP-T7n
227936pLY034bComplementary plasmid providing gIII
227937pBL066cExpress Aβ42-GFP
227938pLY090aSICLOPPS precursor for cyclo-CRVWCAR
227939pLY090bSICLOPPS precursor for cyclo-CRVYQVL
227940pLY071cSICLOPPS precursor for cyclo-CHVVGVI
227941pLY071eSICLOPPS precursor for cyclo-CDLGVFR
227942pLY071fSICLOPPS precursor for cyclo-CRCVFSG

Antibodies from Article