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Efficient Rescue of Retinal Degeneration in Pde6a Mice by Engineered Base Editing and Prime Editing.

Liu Z, Chen S, Davis AE, Lo CH, Wang Q, Li T, Ning K, Zhang Q, Zhao J, Wang S, Sun Y
Adv Sci (Weinh). 2024 Sep 19:e2405628. doi: 10.1002/advs.202405628. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
227416AID-NG-CBEC-to-T base editing in mammalian cells
227417AID-N51A-NG-CBEC-to-T base editing in mammalian cells
227418YEE-NG-CBEC-to-T base editing in mammalian cells
227419TadA-N46L-NG-CBEC-to-T base editing in mammalian cells
227420TadA-NG-CBEC-to-T base editing in mammalian cells
227421AAV-AID-N51A-CBE Nexpresses the N-terminal of AID-N51A-CBE
227422AAV-NG-CBE Cexpresses the C-terminal of AAV-NG-CBE

Antibodies from Article