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Naturally occurring hyperactive variants of human parkin.

Huq TS, Luo J, Fakih R, Sauve V, Gehring K
Commun Biol. 2024 Aug 8;7(1):961. doi: 10.1038/s42003-024-06656-x. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
227352pGEX-parkin P37LFor bacterial expression of hyperactive parkin mutant.
227353pGEX-parkin V224AFor bacterial expression of hyperactive parkin mutant.
227354pGEX-parkin R234QFor bacterial expression of hyperactive parkin mutant.
227355pGEX-parkin R256CFor bacterial expression of hyperactive parkin mutant.
227356pGEX-parkin M458LFor bacterial expression of hyperactive parkin mutant.
227359pGEX-parkin L102KFor bacterial expression of parkin with a mutated ACT.
227360pGEX-parkin T103AFor bacterial expression of parkin with a mutated ACT.
227361pGEX-parkin V105KFor bacterial expression of parkin with a mutated ACT.
227362pGEX-parkin D106AFor bacterial expression of parkin with a mutated ACT.
227364pGEX-parkin delta 101-109For bacterial expression of parkin with a mutated ACT.
227365pGEX-parkin K161NFor bacterial expression of parkin with a mutated pUbl/pUb binding site on RING0.
227366pGEX-parkin Ubl P37LFor bacterial expression of mutated parkin Ubl.
227367pGEX-parkinFor bacterial expression of parkin

Antibodies from Article