Receptor tyrosine kinases, TYRO3, AXL, and MER, demonstrate distinct patterns and complex regulation of ligand-induced activation.

Tsou WI, Nguyen KQ, Calarese DA, Garforth SJ, Antes AL, Smirnov SV, Almo SC, Birge RB, Kotenko SV
J Biol Chem. 2014 Sep 12;289(37):25750-63. doi: 10.1074/jbc.M114.569020. Epub 2014 Jul 29. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

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ID	Plasmid	Purpose
225995	pEF2-FL-hTyro_gR1	Expresses a chimeric contruct having N-terminal human Tyro3 and C-terminal human Interferon Gamma Receptor
225994	pEF2-FL-hAxl_gR1	Expresses a chimeric contruct having N-terminal human Axl and C-terminal human Interferon Gamma Receptor
225993	pEF2-FL-hMer_gR1	Expresses a chimeric contruct having N-terminal human MerTK and C-terminal human Interferon Gamma Receptor