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Prefrontal synaptic regulation of homeostatic sleep pressure revealed through synaptic chemogenetics.

Sawada T, Iino Y, Yoshida K, Okazaki H, Nomura S, Shimizu C, Arima T, Juichi M, Zhou S, Kurabayashi N, Sakurai T, Yagishita S, Yanagisawa M, Toyoizumi T, Kasai H, Shi S
Science. 2024 Sep 27;385(6716):1459-1465. doi: 10.1126/science.adl3043. Epub 2024 Sep 26. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
225827pAAV-hSyn-PSDΔ1,2-FRBx3A component of SYNCit-K (Synapse-targeted chemically induced translocation of Kalirin-7)
225828pAAV-CaMKII(0.3)-mVenus-FKBP-K7GEFA component of SYNCit-K (Synapse-targeted chemically induced translocation of Kalirin-7)

Antibodies from Article