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A fast and responsive voltage indicator with enhanced sensitivity for unitary synaptic events.

Hao YA, Lee S, Roth RH, Natale S, Gomez L, Taxidis J, O'Neill PS, Villette V, Bradley J, Wang Z, Jiang D, Zhang G, Sheng M, Lu D, Boyden E, Delvendahl I, Golshani P, Wernig M, Feldman DE, Ji N, Ding J, Sudhof TC, Clandinin TR, Lin MZ
Neuron. 2024 Sep 17:S0896-6273(24)00643-3. doi: 10.1016/j.neuron.2024.08.019. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
225707pAAV-hsyn-ASAP5-Kv2.1-WPREPan-neuronal soma-targeted expression of the genetically encoded voltage indicator ASAP5
225708pAAV-EF1a-Dio-ASAP5-Kv2.1-WPRECre dependent soma-targeted expression of the genetically encoded voltage indicator ASAP5
225709pAAV-hsyn-ASAP5-WPRECre-dependent pan-membrane expression of the genetically encoded voltage indicator ASAP5, can be used for dendritic voltage imaging

Antibodies from Article