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Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size.

Lin L, Zhao J, Kubota N, Li Z, Lam YL, Nguyen LP, Yang L, Pokharel SP, Blue SM, Yee BA, Chen R, Yeo GW, Chen CW, Chen L, Zheng S
Neuron. 2024 Jul 3;112(13):2157-2176.e12. doi: 10.1016/j.neuron.2024.04.006. Epub 2024 May 1. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
228912pCAGIG-CDKN1AExpression CDKN1A in mammalian cells
228913pCAGIG-shCdkn1a(#4)Knockdown of Cdkn1a in mammalian cells
228915sg_Tada3_i3-ipUSEPR-TR657Knockdown of Tada3 in mammalian cells
228916sg_Tada3_i5-ipUSEPR-TR657Knockdown of Tada3 in mammalian cells
228917sg_Atm_i3-ipUSEPR-TR657Knockdown of Atm in mammalian cells
228918sg_Atm_i5-ipUSEPR-TR657Knockdown of Atm in mammalian cells
228919sg_Gemin2_i1-ipUSEPR-TR657Knockdown of Gemin2 in mammalian cells
228920sg_Gemin2_i5-ipUSEPR-TR657Knockdown of Gemin2 in mammalian cells
228921sg_Brd9_i2-ipUSEPR-TR657Knockdown of Brd9 in mammalian cells
228923sg_Snrpa_i2-ipUSEPR-TR657Knockdown of Snrpa in mammalian cells
228924sg_Snrpa_i4-ipUSEPR-TR657Knockdown of Snrpa in mammalian cells
228926sg_Snrnp48_i4-ipUSEPR-TR657Knockdown of Snrnp48 in mammalian cell
228929sg_Trp53_i3-ipUSEPR-TR657Knockdown of Trp53 in mammalian cells
228930sg_Trp53_i4-ipUSEPR-TR657Knockdown of Trp53 in mammalian cells
228953sg_Cdkn1a_i1-ipUSEPR-TR657Knockdown of Cdkn1a in mammalian cells
228954sg_Cdkn1a_i2-ipUSEPR-TR657Knockdown of Cdkn1a in mammalian cells

Antibodies from Article