Targeted protein degradation via intramolecular bivalent glues.
Hsia O, Hinterndorfer M, Cowan AD, Iso K, Ishida T, Sundaramoorthy R, Nakasone MA, Imrichova H, Schatz C, Rukavina A, Husnjak K, Wegner M, Correa-Saez A, Craigon C, Casement R, Maniaci C, Testa A, Kaulich M, Dikic I, Winter GE, Ciulli A
Nature. 2024 Mar;627(8002):204-211. doi: 10.1038/s41586-024-07089-6. Epub 2024 Feb 21.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 233886 | 10xHis-3C-BRD4(42-459) BD1-BD2 | pRSF-DUET1 for protein overexpression of human BRD4 |
| 233887 | His-GST-TEV-BRD4(42-459) BD1-BD2 | pGex for protein overexpression of human BRD4 |