Thyroid hormone remodels cortex to coordinate body-wide metabolism and exploration.
Hochbaum DR, Hulshof L, Urke A, Wang W, Dubinsky AC, Farnsworth HC, Hakim R, Lin S, Kleinberg G, Robertson K, Park C, Solberg A, Yang Y, Baynard C, Nadaf NM, Beron CC, Girasole AE, Chantranupong L, Cortopassi MD, Prouty S, Geistlinger L, Banks AS, Scanlan TS, Datta SR, Greenberg ME, Boulting GL, Macosko EZ, Sabatini BL
Cell. 2024 Oct 3;187(20):5679-5697.e23. doi: 10.1016/j.cell.2024.07.041. Epub 2024 Aug 22.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 225086 | DRH001_scAAV-hSyn-iCre-HA | Expression of iCre with an HA tag in neurons driven by human synapsin promoter. |
| 225087 | DRH002_scAAV-hSyn-delta_iCre-HA | Expression of inactive delta-iCre (control) with an HA tag in neurons driven by human synapsin promoter. |
| 225088 | DRH015_ AAV-hSyn-WT-THR | Expression of wild-type thyroid receptor beta (THRB, human) with an HA tag in neurons driven by human synapsin promoter. |
| 225089 | DRH016_ AAV-hSyn-DN-THR | Expression of dominant-negative thyroid receptor beta (THRB, human) with an HA tag in neurons driven by human synapsin promoter. |
| 225090 | DRH031_ AAV-SIO-nEF-WT-THR | Cre-dependent expression of wild-type thyroid receptor beta (THRB, human) in neurons driven by nEF promoter. |
| 225091 | DRH032_ AAV-SIO-nEF-DN-THR | Cre-dependent expression of dominant-negative thyroid receptor beta (THRB, human) in neurons driven by nEF promoter. |