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Selective STING stimulation in dendritic cells primes antitumor T cell responses.

Jneid B, Bochnakian A, Hoffmann C, Delisle F, Djacoto E, Sirven P, Denizeau J, Sedlik C, Gerber-Ferder Y, Fiore F, Akyol R, Brousse C, Kramer R, Walters I, Carlioz S, Salmon H, Malissen B, Dalod M, Piaggio E, Manel N
Sci Immunol. 2023 Jan 13;8(79):eabn6612. doi: 10.1126/sciimmunol.abn6612. Epub 2023 Jan 13. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
196623pVAX1-VSVG-INDIANA2Express VSV-G protein in mammalian cells.
196624pVAX1-cGASExpress mouse cGAS protein in mammalian cells.
196625pLentiCRISPRv2_mSTING_gRNA_1Knock-out STING in murine cells, gRNA 1.
196626pLentiCRISPRv2_mSTING_gRNA_2Knock-out STING in murine cells, gRNA 2.
196627pLentiCRISPRv2_mSTING_scrambled_gRNA_1Scrambled control 1 for STING knock-out in murine cells.
196628pLentiCRISPRv2_mSTING_scrambled_gRNA_2Scrambled control 2 for STING knock-out in murine cells.

Antibodies from Article