KLF2 maintains lineage fidelity and suppresses CD8 T cell exhaustion during acute LCMV infection.
Fagerberg E, Attanasio J, Dien C, Singh J, Kessler EA, Abdullah L, Shen J, Hunt BG, Connolly KA, De Brouwer E, He J, Iyer NR, Buck J, Borr ER, Damo M, Foster GG, Giles JR, Huang YH, Tsang JS, Krishnaswamy S, Cui W, Joshi NS
Science. 2025 Jan 2;387(6735):eadn2337. doi: 10.1126/science.adn2337. Epub 2025 Feb 14.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 224294 | U6-PGK-hCD2 | Expresses sgRNA from U6 promoter and human CD2 under PGK |
| 224295 | EF1a-KLF2-T2A-mCHERRY | Expresses mouse KLF2 and mCherry under EF1a promoter |
| 224296 | EF1a-TBET-T2A-mCHERRY | Expresses mouse TBET and mCherry under EF1a promoter |
| 224297 | EF1a-ER-KLF2-T2A-mCHERRY | Expresses estrogen receptor linked KLF2 and mCherry under EF1a promoter |
| 224298 | EF1a-mCHERRY | Expresses mCherry under EF1a promoter (CTRL vector) |