Sequential activation of E2F via Rb degradation and c-Myc drives resistance to CDK4/6 inhibitors in breast cancer.
Kim S, Armand J, Safonov A, Zhang M, Soni RK, Schwartz G, McGuinness JE, Hibshoosh H, Razavi P, Kim M, Chandarlapaty S, Yang HW
Cell Rep. 2023 Nov 28;42(11):113198. doi: 10.1016/j.celrep.2023.113198. Epub 2023 Oct 21.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 223959 | pLV-H2B-iRFP670-p2a-mCerulean-Geminin (1–110)-IRES-Neomycin | Dual fluorescent reporter for histone H2B and for APC/C activity |
| 223962 | pLV-H2B-iRFP670-p2a-YFP-Rb-IRES-blasticidin | Dual fluorescent reporter for histone H2B and for exogenous Rb |