Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease.
Mehta RS, Mayers JR, Zhang Y, Bhosle A, Glasser NR, Nguyen LH, Ma W, Bae S, Branck T, Song K, Sebastian L, Pacheco JA, Seo HS, Clish C, Dhe-Paganon S, Ananthakrishnan AN, Franzosa EA, Balskus EP, Chan AT, Huttenhower C
Nat Med. 2023 Mar;29(3):700-709. doi: 10.1038/s41591-023-02217-7. Epub 2023 Feb 23.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 223434 | pET-28b C7H1G6_6H N-terminal | C7H1G6 GNAT expression vector with N-terminal His6 tag |
| 223435 | pET-28b R6CZ24_6H C-terminal | R6CZ24 Thiolase expression vector with C-terminal His6 tag |
| 223436 | pET-28b Salmonella NAT_6H C-terminal | Salmonella NAT expression vector with C-terminal His6 tag |