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Enhancer-AAVs allow genetic access to oligodendrocytes and diverse populations of astrocytes across species
Mich JK, Sunil S, Johansen N, Martinez RA, Leytze M, Gore BB, Mahoney JT, Ben-Simon Y, Bishaw Y, Brouner K, Campos J, Canfield R, Casper T, Dee N, Egdorf T, Gary A, Gibson S, Goldy J, Groce EL, Hirschstein D, Loftus L, Lusk N, Malone J, Martin NX, Monet D, Omstead V, Opitz-Araya X, Oster A, Pom CA, Potekhina L, Reding M, Rimorin C, Ruiz A, Sedeño-Cortés AE, Shapovalova NV, Taormina M, Taskin N, Tieu M, Valera Cuevas NJ, Weed N, Way S, Yao Z, McMillen DA, Kunst M, McGraw M, Thyagarajan B, Waters J, Bakken TE, Yao S, Smith KA, Svoboda K, Podgorski K, Kojima Y, Horwitz GD, Zeng H, Daigle TL, Lein ES, Tasic B, Ting JT, Levi BP
bioRxiv 2023.09.20.558718 Article

Plasmids from Article

ID Plasmid Purpose
208120CN2979-rAAV-eHGT_361h-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in astrocytes AAV Virus
208121CN2141-rAAV-eHGT_371h-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in astrocytes AAV Virus
208122CN2144-rAAV-eHGT_376h-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in astrocytes AAV Virus
208123CN3098-pAAV-eHGT_380h-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in astrocytes AAV Virus
208124CN2146-rAAV-eHGT_381h-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in astrocytes AAV Virus
208125CN2495-rAAV-eHGT_385h-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in astrocytes AAV Virus
208126CN2153-rAAV-eHGT_390h-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in astrocytes AAV Virus
208128CN2084-rAAV-eHGT_373m-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in astrocytes AAV Virus
208129CN2098-rAAV-eHGT_374m-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in astrocytes AAV Virus
208130CN2085-rAAV-eHGT_375m-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in astrocytes AAV Virus
208131CN2122-rAAV-eHGT_385m-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in astrocytes AAV Virus
208132CN2088-rAAV-eHGT_386m-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in astrocytes AAV Virus
208133CN2102-rAAV-eHGT_387m-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in astrocytes AAV Virus
208134CN2089-rAAV-eHGT_390m-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in astrocytes AAV Virus
208135AiP1346-pAAV-MGT_E117-minBGpromoter-SYFP2-WPRE3-bGHpADirect-expressing SYFP2 in astrocytes AAV Virus. Alias: AiP1346 - pAAV-AiE2117m-minBG-SYFP2-WPRE-BGHpA
208136AiP1347-pAAV-MGT_E118-minBGpromoter-SYFP2-WPRE3-bGHpADirect-expressing SYFP2 in astrocytes AAV Virus. Alias: AiP1347 - pAAV-AiE2118m-minBG-SYFP2-WPRE-BGHpA
208137AiP1349-pAAV-MGT_E120-minBGpromoter-SYFP2-WPRE3-bGHpADirect-expressing SYFP2 in astrocytes AAV Virus. Alias: AiP1349 - pAAV-AiE2120m-minBG-SYFP2-WPRE-BGHpA
208138AiP1457-pAAV-MGT_E121-minBGpromoter-SYFP2-WPRE3-bGHpADirect-expressing SYFP2 in astrocytes AAV Virus. Alias: AiP1457 - pAAV-AiE2121m-minBG-SYFP2-WPRE-BGHpA
208140AiP1389-pAAV-MGT_E160-minBGpromoter-SYFP2-WPRE3-bGHpADirect-expressing SYFP2 in astrocytes AAV Virus. Alias: AiP1389 - pAAV-AiE2160m-minBG-SYFP2-WPRE-BGHpA
208141CN2558-rAAV-3xCore2(390m)-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in astrocytes AAV Virus
208142CN3568-rAAV-3xcore1(387m)-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in astrocytes AAV Virus
208143CN3572-rAAV-3xcore2(390h)-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in astrocytes AAV Virus
208144CN2556-rAAV-3xCore(410m)-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in oligodendrocytes AAV Virus
208145CN2505-rAAV-eHGT_391h-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in oligodendrocytes AAV Virus
208146CN2157-rAAV-eHGT_395h-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in oligodendrocytes AAV Virus
208147CN2498-rAAV-eHGT_395m-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in oligodendrocytes AAV Virus
208148CN2158-rAAV-eHGT_396h-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in oligodendrocytes AAV Virus
208149CN2099-rAAV-eHGT_396m-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in oligodendrocytes AAV Virus
208150CN2123-rAAV-eHGT_397m-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in oligodendrocytes AAV Virus
208151CN2162-rAAV-eHGT_400h-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in oligodendrocytes AAV Virus
208152CN2106-rAAV-eHGT_400m-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in oligodendrocytes AAV Virus
208153CN2677-rAAV-eHGT_401h-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in oligodendrocytes AAV Virus
208154CN2499-rAAV-eHGT_403h-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in oligodendrocytes AAV Virus
208155CN2107-rAAV-eHGT_405m-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in oligodendrocytes AAV Virus
208156CN3062-pAAV-eHGT_409h-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in oligodendrocytes AAV Virus
208157CN2109-rAAV-eHGT_410m-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in oligodendrocytes AAV Virus
208158CN2845-rAAV-eHGT_641m-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in oligodendrocytes AAV Virus
208165CN4253-rAAV-3xCore2_eHGT_380h-minBglobin-SYFP2-WPRE3-BGHpADirect-expressing SYFP2 in astrocytes AAV Virus
214492AiP1421 - pAAV-AiE2119m-minBG-SYFP2-WPRE-BGHpAAiE2119m is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cells
214493AiP1422 - pAAV-AiE2123m-minBG-SYFP2-WPRE-BGHpAAiE2123m is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cells

Antibodies from Article