Role of the circadian nuclear receptor REV-ERBalpha in dorsal raphe serotonin synthesis in mood regulation.
Park I, Choi M, Kim J, Jang S, Kim D, Kim J, Choe Y, Geum D, Yu SW, Choi JW, Moon C, Choe HK, Son GH, Kim K
Commun Biol. 2024 Aug 15;7(1):998. doi: 10.1038/s42003-024-06647-y.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 223226 | pAAV-U6-sgRev-erba-hSyn-mCherry-KASH | guideRNA targeting the mouse Rev-erb alpha (Nr1d1) |
| 223227 | pAAV-U6-sgPet-1-hSyn-mCherry-KASH | guideRNA targeting the mouse Pet-1 (Fev) |
| 223526 | hTph2p-Luc | Firefly-luciferase reporter expression driven by human Tph2 promoter |
| 223663 | mTph2p(330bp)-Luc | Firefly-luciferase reporter expression driven by proximal 330-bp of mouse Tph2 promoter |
| 223664 | mTph2p(330bp)-mut1-Luc | Firefly-luciferase reporter expression driven by proximal 330-bp of mouse Tph2 promoter point mutation at RRE site 1 |
| 223665 | mTph2p(330bp)-mut2-Luc | Firefly-luciferase reporter expression driven by proximal 330-bp of mouse Tph2 promoter point mutation at RRE site 2 |
| 223666 | mTph2p(330bp)-mut3-Luc | Firefly-luciferase reporter expression driven by proximal 330-bp of mouse Tph2 promoter point mutation at PRE site 3 |
| 223667 | mTph2p(330bp)-mut4-Luc | Firefly-luciferase reporter expression driven by proximal 330-bp of mouse Tph2 promoter point mutation at PRE site 4 |