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HAND1 level controls the specification of multipotent cardiac and extraembryonic progenitors from human pluripotent stem cells.

Lynch AT, Phillips N, Douglas M, Dorgnach M, Lin IH, Adamson AD, Darieva Z, Whittle J, Hanley NA, Bobola N, Birket MJ
EMBO J. 2025 Mar 31. doi: 10.1038/s44318-025-00409-0. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
223190pSOX17-T2A-dTom-PGK-NeoTomato reporter plasmid targeting the human SOX17 gene
223191pFOXA2-T2A-mTagBFP2-PGK-NeoBFP reporter plasmid targeting the human FOXA2 gene
223192pENTR-FLAG-HAND1-T2A-mTagBFP2Entry vector containing FLAG-HAND1 with a T2A-mTagBFP2 reporter (attL flanked)
223216pHAND1-AM-Tag-PGK-NeoTargeting plasmid for inserting a C-terminal AM-Tag in the human HAND1 gene

Antibodies from Article