VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates.
Mirsanaye AS, Hoffmann S, Weisser M, Mund A, Lopez Mendez B, Typas D, van den Boom J, Benedict B, Hendriks IA, Nielsen ML, Meyer H, Duxin JP, Montoya G, Mailand N
Nat Commun. 2024 Mar 19;15(1):2459. doi: 10.1038/s41467-024-46760-4.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 223018 | GFP-VCF1 WT | Expression of GFP-tagged VCF1 in mammalian cells. |
| 223019 | GFP-VCF1 N167A | Expression of GFP-tagged VCF1 (p97 binding-deficient N167A mutant) in mammalian cells. |
| 223020 | Strep-HA-VCF1 WT | Expression of Strep-HA-tagged VCF1 in mammalian cells. |
| 223021 | Strep-HA-VCF1 N167A | Expression of Strep-HA-tagged VCF1 (p97 binding-deficient N167A mutant) in mammalian cells. |