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Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR-Cas9 RNP.

Chen K, Han H, Zhao S, Xu B, Yin B, Trinidad M, Burgstone BW, Murthy N, Doudna JA
bioRxiv [Preprint]. 2023 Nov 15:2023.11.15.566339. doi: 10.1101/2023.11.15.566339. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
222987CL7_2xNLS_iGeoCas9(C1)_2xNLS_HisBacterial expression of iGeoCas9(C1) construct
222989CL7_2xNLS_iGeoCas9(G)_2xNLS_HisBacterial expression of iGeoCas9(G) construct
222990His-CL7_MBP_1xNLS_iGeoCas9(C1)_2xNLS(star)Bacterial expression of iGeoCas9(C1) construct
222991His-CL7_MBP_1xNLS_iGeoCas9(C2)_2xNLS(star)Bacterial expression of iGeoCas9(C2) construct

Antibodies from Article