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Engineering self-deliverable ribonucleoproteins for genome editing in the brain.

Chen K, Stahl EC, Kang MH, Xu B, Allen R, Trinidad M, Doudna JA
Nat Commun. 2024 Feb 26;15(1):1727. doi: 10.1038/s41467-024-45998-2. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
222970His-CL7-2NLS-SpyCas9(dS)-A22p3starBacterial expression of A22p-fused SpyCas9 construct
222971His_CL7_2NLS_iCas12a-4NLSBacterial expression of NLS-rich iCas12a construct

Antibodies from Article