ABE-ultramax for high-efficiency biallelic adenine base editing in zebrafish.
Qin W, Liang F, Lin SJ, Petree C, Huang K, Zhang Y, Li L, Varshney P, Mourrain P, Liu Y, Varshney GK
Nat Commun. 2024 Jul 4;15(1):5613. doi: 10.1038/s41467-024-49943-1.
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 222138 | pT3TS-spCas9 ABE-Umax | Adenine base editor with modified TadA variant for A-to-G base editing in zebrafish |
| 222139 | pT3TS-spRYCas9-ABE-UMax | Near PAMless Adenine base editor with modified TadA variant for A-to-G base editing in zebrafish |
| 222140 | pT3TS-spCas9 ABE-Umax-ex1-rest1 | Adenine base editor with modified TadA variant for extended window and restricted A-to-G base editing in zebrafish |
| 222141 | pT3TS-spCas9 ABE-Umax-ex1 | Adenine base editor with modified TadA variant for extended window for A-to-G base editing in zebrafish |
| 222142 | pcs2+spCas9 ABE-Umax-nanos | Adenine base editor with modified TadA variant for germline A-to-G base editing in zebrafish |
| 222143 | pT3TS-spCas9 ABE-Umax-ex2-rest1 | Adenine base editor with modified TadA variant for extended window and restricted A-to-G base editing in zebrafish |
| 222144 | pT3TS-spCas9-ABE-Umax-rest1 | Adenine base editor with modified TadA variant for restricted A-to-G base editing in zebrafish |