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ABE-ultramax for high-efficiency biallelic adenine base editing in zebrafish.

Qin W, Liang F, Lin SJ, Petree C, Huang K, Zhang Y, Li L, Varshney P, Mourrain P, Liu Y, Varshney GK
Nat Commun. 2024 Jul 4;15(1):5613. doi: 10.1038/s41467-024-49943-1. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
222140pT3TS-spCas9 ABE-Umax-ex1-rest1Adenine base editor with modified TadA variant for extended window and restricted A-to-G base editing in zebrafish
222143pT3TS-spCas9 ABE-Umax-ex2-rest1Adenine base editor with modified TadA variant for extended window and restricted A-to-G base editing in zebrafish
222144pT3TS-spCas9-ABE-Umax-rest1Adenine base editor with modified TadA variant for restricted A-to-G base editing in zebrafish

Antibodies from Article