Unconstrained Precision Mitochondrial Genome Editing with alphaDdCBEs.
Castillo SR, Simone BW, Clark KJ, Devaux P, Ekker SC
Hum Gene Ther. 2024 Sep 24. doi: 10.1089/hum.2024.073.
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PubMed
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 221931 | FusX DdCBE 1397C | Backbone plasmid for FusX-based assembly of DdCBE arm with DddAtox 1397C |
| 221932 | FusX DdCBE 1397N | Backbone plasmid for FusX-based assembly of DdCBE arm with DddAtox 1397N |
| 221933 | FusX DdCBE DddA6-11 1397C | Backbone plasmid for FusX-based assembly of DdCBE arm with DddA6/11 1397C |
| 221934 | FusX DdCBE DddA6 1397N | Backbone plasmid for FusX-based assembly of DdCBE arm with DddA6 1397N |
| 221935 | FusX DdCBE DddA11 1397N | Backbone plasmid for FusX-based assembly of DdCBE arm with DddA11 1397N |
| 221936 | FusX alphaDdCBE 1397C | Backbone plasmid for FusX-based assembly of alphaDdCBE arm with DddAtox 1397C |
| 221937 | FusX alphaDdCBE 1397N | Backbone plasmid for FusX-based assembly of alphaDdCBE arm with DddAtox 1397N |
| 221938 | FusX alphaDdCBE DddA6-11 1397C | Backbone plasmid for FusX-based assembly of alphaDdCBE arm with DddA6/11 1397C |
| 221939 | FusX alphaDdCBE DddA6 1397N | Backbone plasmid for FusX-based assembly of alphaDdCBE arm with DddA6 1397N |
| 221940 | FusX alphaDdCBE DddA11 1397N | Backbone plasmid for FusX-based assembly of alphaDdCBE arm with DddA11 1397N |
| 221941 | TALE-free DddAtox 1397C | Expresses mitochondrially targeted TALE-free DddAtox 1397C-UGI in mammalian cells |
| 221942 | TALE-free DddAtox 1397N | Expresses mitochondrially targeted TALE-free DddAtox 1397N-UGI in mammalian cells |
| 221943 | TALE-free DddA6-11 1397C | Expresses mitochondrially targeted TALE-free DddA6/11 1397C-UGI in mammalian cells |
| 221944 | TALE-free DddA6 1397N | Expresses mitochondrially targeted TALE-free DddA6 1397N-UGI in mammalian cells |
| 221945 | TALE-free DddA11 1397N | Expresses mitochondrially targeted TALE-free DddA11 1397N-UGI in mammalian cells |
| 221946 | ATP6 DdCBE A1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221947 | ATP6 DdCBE A2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221948 | ATP6 DdCBE C1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221949 | ATP6 DdCBE C2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221950 | ATP6 DdCBE G1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221951 | ATP6 DdCBE G2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221952 | ATP6 DdCBE T1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221953 | ATP6 DdCBE T2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221954 | ATP6 alphaDdCBE A1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221955 | ATP6 alphaDdCBE A2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221956 | ATP6 alphaDdCBE C1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221957 | ATP6 alphaDdCBE C2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221958 | ATP6 alphaDdCBE G1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221959 | ATP6 alphaDdCBE G2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221960 | ATP6 alphaDdCBE T1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221961 | ATP6 alphaDdCBE T2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221962 | CO1 DdCBE C1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221963 | CO1 DdCBE A2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221964 | CO1 DdCBE T1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221965 | CO1 DdCBE T2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221966 | CO1 alphaDdCBE C1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221967 | CO1 alphaDdCBE A2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221968 | CO1 alphaDdCBE T1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221969 | CO1 alphaDdCBE T2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221970 | ND2 DdCBE C1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221971 | ND2 DdCBE A2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221972 | ND2 DdCBE T1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221973 | ND2 DdCBE T2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221974 | ND2 alphaDdCBE C1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221975 | ND2 alphaDdCBE A2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221976 | ND2 alphaDdCBE T1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221977 | ND2 alphaDdCBE T2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221978 | ND4 DdCBE G1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221979 | ND4 DdCBE C2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221980 | ND4 DdCBE T1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221981 | ND4 DdCBE T2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221982 | ND4 alphaDdCBE G1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221983 | ND4 alphaDdCBE C2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221984 | ND4 alphaDdCBE T1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221985 | ND4 alphaDdCBE T2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221986 | TC mDdCBE A1 | Expresses monomeric mitochondrial cytosine base editor in mammalian cells |
| 221987 | TC mDdCBE T2 | Expresses monomeric mitochondrial cytosine base editor in mammalian cells |
| 221988 | TC DdCBE A1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221989 | TC DdCBE T2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221990 | TC alphaDdCBE A1 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221991 | TC alphaDdCBE T2 | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221992 | TL1 DdCBE A1 (DddA6-C) | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221993 | TL1 DdCBE T2 (DddA6-N) | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221994 | TL1 alphaDdCBE A1 (DddA6-C) - TL1 alphaL_DdCBE 2 (left, DddA11-C) | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221995 | TL1 alphaDdCBE T2 (DddA6-N) | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221996 | TL1 alphaL_DdCBE 1 (left, DddA11-C) | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221997 | TL1 alphaL_DdCBE 1-2-3 (right, DddA11-N) | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221998 | TL1 alphaL_DdCBE 3-4 (left, DddA11-C) - TL1 alphaDdCBE 1 (left, DddA11-C) | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 221999 | TL1 alphaL_DdCBE 4 (right, DddA11-N) | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 222000 | TL1 alphaDdCBE 1-2 (right, DddA11-N) | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 222001 | TL1 alphaDdCBE 2 (left, DddA11-C) | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 222002 | TL1 alphaDdCBE 3_CN (left, DddA11-C) | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 222003 | TL1 alphaDdCBE 3_CN (right, DddA11-N) | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 222004 | TL1 alphaDdCBE 3_NC (left, DddA11-N) | Expresses mitochondrial cytosine base editor arm in mammalian cells |
| 222005 | TL1 alphaDdCBE 3_NC (right, DddA11-C) | Expresses mitochondrial cytosine base editor arm in mammalian cells |