Design of highly functional genome editors by modeling the universe of CRISPR-Cas sequences
Ruffolo JA, Nayfach S, Gallagher J, Bhatnagar A, Beazer J, Hussain R, Russ J, Yip J, Hill E, Pacesa M, Meeske AJ, Cameron P, Madani A
bioRxiv 2024.04.22.590591
(Link opens in a new window)
Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 221566 | OpenCRISPR-1 sgRNA-16nt stem | Express OpenCRISPR-1 sgRNA (16nt stem loop) in human cells using a U6 promoter. Plasmid also encodes a CMV-driven GFP reporter. |
| 221567 | OpenCRISPR-1 sgRNA-12nt stem | Express OpenCRISPR-1 sgRNA (12nt stem loop) in human cells using a U6 promoter. Plasmid also encodes a CMV-driven GFP reporter. |