Ligand binding initiates single-molecule integrin conformational activation.
Li J, Jo MH, Yan J, Hall T, Lee J, Lopez-Sanchez U, Yan S, Ha T, Springer TA
Cell. 2024 May 14:S0092-8674(24)00475-6. doi: 10.1016/j.cell.2024.04.049.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 221394 | PD2529 human alpha5 ecto | Mammalian expression of human integrin alpha5 ectodomain |
| 221395 | PD2529 human alpha5 full | Mammalian expression of human integrin alpha5 full length |
| 221396 | pcDNA3.4 human alpha5 full | Mammalian expression of human integrin alpha5 full length |
| 221399 | Beta1 Q280* K418* ectodomain | Mammalian expression of human integrin beta1 Q280* K418* ectodomain |
| 221400 | Beta1 N391* N562* ectodomain | Mammalian expression of human integrin beta1 N391* N562* ectodomain |
| 221401 | PD2529 human beta1 full | Mammalian expression of human integrin beta1 full-length |
| 221402 | Beta1 Q280* full-length | Mammalian expression of human integrin beta1 Q280* full-length |
| 221403 | Beta1 K418* full-length | Mammalian expression of human integrin beta1 K418* full-length |
| 221404 | Beta1 N391* full-length | Mammalian expression of human integrin beta1 N391* full-length |
| 221405 | Beta1 N562* full-length | Mammalian expression of human integrin beta1 N562* full-length |
| 221406 | Beta1 Q280* K418* full-length | Mammalian expression of human integrin beta1 Q280* K418* full-length |
| 221407 | Beta1 N391* N562* full-length | Mammalian expression of human integrin beta1 N391* N562* full-length |
| 221408 | Talin1 head EGFP fusion | Mammalian expression of Talin1 head EGFP fusion for mammalian expression |