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The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination.

O'Donnell L, Panier S, Wildenhain J, Tkach JM, Al-Hakim A, Landry MC, Escribano-Diaz C, Szilard RK, Young JT, Munro M, Canny MD, Kolas NK, Zhang W, Harding SM, Ylanko J, Mendez M, Mullin M, Sun T, Habermann B, Datti A, Bristow RG, Gingras AC, Tyers MD, Brown GW, Durocher D
Mol Cell. 2010 Nov 24;40(4):619-31. doi: 10.1016/j.molcel.2010.10.024. Epub 2010 Nov 4. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
221011pDNA5-FRT/TO-FLAG-TONSLmammalian expression vector of Flag tagged TONSL siRNA resistant
221012pDNA5-FRT/TO-eGFP-TONSLmammalian expression vector of eGFP tagged TONSL siRNA resistant
221013pMMS22L-siR3mammalian expression vector of myc-Flag tagged MMS22L siRNA resistant
221014pcDNA5-FRT/TO-eGFP-msMMS22Lmammalian expression vector of eGFP tagged mouse MMS22L
221015pcDNA5-FRT/TO-FLAG-msMMS22Lmammalian expression vector of Flag tagged mouse MMS22L

Antibodies from Article