Development of deaminase-free T-to-S base editor and C-to-G base editor by engineered human uracil DNA glycosylase
Tong, H., Wang, H., Wang, X. et al.
Nat Commun 15
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Article
Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
220617 | gCBEv2 | vector for encoding an engineered glycosylase-based cytosine (C) base editor (gCBEv2) driven by EF1a promoter, guide RNAs compatible with SpCas9 driven by hU6, mCherry driven by CBh promoter |
220618 | gCBEv3 | vector for encoding an engineered glycosylase-based cytosine (C) base editor (gCBEv3) driven by EF1a promoter, guide RNAs compatible with SpG driven by hU6, mCherry driven by CBh promoter |
220619 | gTBEv3 | vector for encoding an engineered glycosylase-based thymine (T) base editor (gTBEv3) driven by EF1a promoter, guide RNAs compatible with SpCas9 driven by hU6, mCherry driven by CBh promoter |
220620 | gTBEv4 | vector for encoding an engineered glycosylase-based thymine (T) base editor (gTBEv4) driven by EF1a promoter, guide RNAs compatible with SpCas9 driven by hU6, mCherry driven by CBh promoter |
220621 | gTBEv5 | vector for encoding an engineered glycosylase-based thymine (T) base editor (gTBEv5) driven by EF1a promoter, guide RNAs compatible with SpCas9 driven by hU6, mCherry driven by CBh promoter |