Programmed RNA editing with an evolved bacterial adenosine deaminase.
Yan H, Tang W
Nat Chem Biol. 2024 Jul 5. doi: 10.1038/s41589-024-01661-x.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
219545 | DECOR | Expression of CMV-TadA8e-NLS-dCas13d-NLS in mammalian cells (DECOR expression) |
219546 | hfDECOR-F148A | Expression of CMV-TadA8e-F148A-NLS-dCas13d-NLS in mammalian cells (hfDECOR-F148A expression) |
219547 | hfDECOR-V106G | Expression of CMV-TadA8e-V106G-NLS-dCas13d-NLS in mammalian cells (hfDECOR-V106G expression) |
219655 | CasRx gRNA targeting EZH2 | hU6-driven expression of CasRx guide RNA targeting EZH2. 5' processed DR followed by EZH2 guide. |