Travis Stracker Lab: Identification of de novo mutations in TLK1 and MDM1 in a patient with a neurodevelopmental disorder and immunodeficiency

Unpublished

Plasmids from Article

ID	Plasmid	Purpose
218829	pLPC-C-SF-TAP-DEST-TLK1-WT	Expresses C-terminal Strep-FLAG-tagged wild type human TLK1 variant 5 in a retrovirus vector.
218830	pLPC-C-SF-TAP-DEST-TLK1- Q479E	Expresses C-terminal Strep-FLAG-tagged Q479E human TLK1 variant 5 in a retrovirus vector.
218831	pLPC-C-SF-TAP-DEST-TLK1- M566T	Expresses C-terminal Strep-FLAG-tagged M566T human TLK1 variant 5 in a retrovirus vector.
218832	pcDNA5/FRT/TO-N-FLAG-hBirA*-TLK1-M566T	Expresses N-terminal BirA*-tagged human TLK1 variant 5 mutant M566T for BioID experiments.
218833	pcDNA5/FRT/TO-N-FLAG-hBirA*-TLK1-Q479E	Expresses N-terminal BirA*-tagged human TLK1 variant 5 mutant Q479E for BioID experiments.
218834	pcDNA5/FRT/TO-N-FLAG-hBirA*-TLK1-WT	Expresses N-terminal BirA*-tagged human wild type TLK1 variant 5 for BioID experiments.
218835	N-SF-TAP-DEST-TLK2-D592V	Expresses N-terminal Strep-FLAG-tagged human TLK2 mutant D592V (kinase dead).