Lysosomal damage sensing and lysophagy initiation by SPG20-ITCH.
Gahlot P, Kravic B, Rota G, van den Boom J, Levantovsky S, Schulze N, Maspero E, Polo S, Behrends C, Meyer H
Mol Cell. 2024 Mar 14:S1097-2765(24)00172-2. doi: 10.1016/j.molcel.2024.02.029.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 218578 | peGFP C3-SPG20 | Expresses GFP-tagged human SPG20 in mammalian cells |
| 218579 | peGFP C3-SPG20 8xV | Expresses GFP-tagged human SPG20 bulky hydrophobic amino acid mutant in mammalian cells |
| 218580 | peGFP C1-SPG20 SC domain | Expresses GFP-tagged SC domain of human SPG20 in mammalian cells |
| 218581 | peGFP C3-SPG20-PAAA | Expresses GFP-tagged PPAY motif mutant (PAAA) of human SPG20 in mammalian cells; this mutant does not interact with ITCH |
| 218582 | peGFP C2-IST1 | Expresses GFP-tagged human IST1 in mammalian cells |