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Fibroblast activation protein drives tumor metastasis via a protease-independent role in invadopodia stabilization.

Bukhari M, Patel N, Fontana R, Santiago-Medina M, Jiang Y, Li D, Pestonjamasp K, Christiansen VJ, Jackson KW, McKee PA, Yang J
Cell Rep. 2023 Oct 31;42(10):113302. doi: 10.1016/j.celrep.2023.113302. Epub 2023 Oct 19. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
207402pWZL-Blast FAP S624AExpresses the S624A mutant of FAP (Fibroblast Activation Protein), which shows no protease activity.
207403pWZL-Blast FAP A657SExpresses the A657S mutant of FAP (Fibroblast Activation Protein), which shows partial protease activity.
210643pWZL-Blast FAPwtExpresses the FAP (Fibroblast Activation Protein) protein.

Antibodies from Article