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CRISPR mediated transactivation in the human disease vector Aedes aegypti.

Bui M, Dalla Benetta E, Dong Y, Zhao Y, Yang T, Li M, Antoshechkin IA, Buchman A, Bottino-Rojas V, James AA, Perry MW, Dimopoulos G, Akbari OS
PLoS Pathog. 2023 Jan 19;19(1):e1010842. doi: 10.1371/journal.ppat.1010842. eCollection 2023 Jan. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
183993OA-986F (AAEL003877-dCas9-VPR)Expresses dCas9-VPR under the Ae. aegypti polyubiquitin promoter
184006OA-1053A Expresses arrays of gRNA targeting eve promoter under U6b/c promoter
184007OA-1053BExpresses arrays of gRNA targeting hh promoter under U6b/c promoter
190997OA-1127BExpresses arrays of gRNA targeting rel1 promoter under U6b/c promoter

Antibodies from Article