IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus.
Guney MH, Nagalekshmi K, McCauley SM, Carbone C, Aydemir O, Luban J
Proc Natl Acad Sci U S A. 2024 Jul 16;121(29):e2404349121. doi: 10.1073/pnas.2404349121. Epub 2024 Jul 10.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 174221 | pPU-HSA-miR30-L1221 | All-in-one control rescue-control shRNA knockdown vector |
| 174222 | pPU-HSA-miR30-MDA5 | All-in-one control rescue-MDA5 shRNA knockdown vector |
| 174223 | pPU-huMDA5-miR30-L1221 | All-in-one huMDA5 rescue-control shRNA knockdown vector |
| 174224 | pPU-huMDA5-miR30-MDA5 | All-in-one huMDA5 rescue-MDA5 shRNA knockdown vector |
| 174225 | pscALPSpuro-MDA5delta2CARD | Expresses human MDA5 that lacks 2 CARD domains |
| 174226 | pscALPSpuro-MDA5-S88D | Expresses human MDA5 S88D mutant |
| 174227 | pscALPSpuro-MDA5-S88E | Expresses human MDA5 S88E mutant |
| 174228 | pscALPSpuro-Nipah V | Expresses Nipah virus V |
| 174229 | pAPM-miR30-CAPRIN1-ts1 | CAPRIN1 knockdown |
| 174230 | pAPM-miR30-CAPRIN1-ts2 | CAPRIN1 knockdown |
| 174231 | pAPM-miR30-CAPRIN1-ts3 | CAPRIN1 knockdown |
| 174232 | pAPM-miR30-DDX1-ts1 | DDX1 knockdown |
| 174233 | pAPM-miR30-DDX1-ts2 | DDX1 knockdown |
| 174234 | pAPM-miR30-DDX1-ts3 | DDX1 knockdown |
| 174235 | pAPM-miR30-DDX3X-ts1 | DDX3X knockdown |
| 174236 | pAPM-miR30-DDX3X-ts2 | DDX3X knockdown |
| 174237 | pAPM-miR30-DDX3X-ts3 | DDX3X knockdown |
| 174238 | pAPM-miR30-DDX17-ts1 | DDX17 knockdown |
| 174239 | pAPM-miR30-DDX17-ts2 | DDX17 knockdown |
| 174240 | pAPM-miR30-DDX17-ts3 | DDX17 knockdown |
| 174241 | pAPM-miR30-DDX58-ts1 | DDX58 knockdown |
| 174242 | pAPM-miR30-DDX58-ts2 | DDX58 knockdown |
| 174243 | pAPM-miR30-DDX58-ts3 | DDX58 knockdown |
| 174244 | pAPM-miR30-DHX58-ts1 | DHX58 knockdown |
| 174245 | pAPM-miR30-DHX58-ts2 | DHX58 knockdown |
| 174246 | pAPM-miR30-DHX58-ts3 | DHX58 knockdown |
| 174247 | pAPM-miR30-EIF2AK2-ts1 | EIF2AK2 knockdown |
| 174248 | pAPM-miR30-EIF2AK2-ts2 | EIF2AK2 knockdown |
| 174249 | pAPM-miR30-EIF2AK2-ts3 | EIF2AK2 knockdown |
| 174250 | pAPM-miR30-HNRNPK-ts1 | HNRNPK knockdown |
| 174251 | pAPM-miR30-HNRNPK-ts2 | HNRNPK knockdown |
| 174252 | pAPM-miR30-HNRNPK-ts3 | HNRNPK knockdown |
| 174253 | pAPM-miR30-HNRNPR-ts1 | HNRNPR knockdown |
| 174254 | pAPM-miR30-HNRNPR-ts2 | HNRNPR knockdown |
| 174255 | pAPM-miR30-HNRNPR-ts3 | HNRNPR knockdown |
| 174256 | pAPM-miR30-IFI16-ts1 | IFI16 knockdown |
| 174257 | pAPM-miR30-IFI16-ts2 | IFI16 knockdown |
| 174258 | pAPM-miR30-IFI16-ts3 | IFI16 knockdown |
| 174259 | pAPM-miR30-IFIH1-ts1 | IFIH1 knockdown |
| 174260 | pAPM-miR30-IFIH1-ts2 | IFIH1 knockdown |
| 174261 | pAPM-miR30-IFIH1-ts3 | IFIH1 knockdown |
| 174262 | pAPM-miR30-ILF2-ts1 | ILF2 knockdown |
| 174263 | pAPM-miR30-ILF2-ts2 | ILF2 knockdown |
| 174264 | pAPM-miR30-ILF2-ts3 | ILF2 knockdown |
| 174265 | pAPM-miR30-ILF3-ts1 | ILF3 knockdown |
| 174266 | pAPM-miR30-ILF3-ts2 | ILF3 knockdown |
| 174267 | pAPM-miR30-ILF3-ts3 | ILF3 knockdown |
| 174268 | pAPM-miR30-LRPPRC-ts1 | LRPPRC knockdown |
| 174269 | pAPM-miR30-LRPPRC-ts2 | LRPPRC knockdown |
| 174270 | pAPM-miR30-LRPPRC-ts3 | LRPPRC knockdown |
| 174271 | pAPM-miR30-MATR3-ts1 | MATR3 knockdown |
| 174272 | pAPM-miR30-MATR3-ts2 | MATR3 knockdown |
| 174273 | pAPM-miR30-MATR3-ts3 | MATR3 knockdown |
| 174274 | pAPM-miR30-MAVS-ts1 | MAVS knockdown |
| 174275 | pAPM-miR30-MAVS-ts2 | MAVS knockdown |
| 174276 | pAPM-miR30-MAVS-ts3 | MAVS knockdown |
| 174277 | pAPM-miR30-MOV10-ts1 | MOV10 knockdown |
| 174278 | pAPM-miR30-MOV10-ts2 | MOV10 knockdown |
| 174279 | pAPM-miR30-MOV10-ts3 | MOV10 knockdown |
| 174280 | pAPM-miR30-MYD88-ts1 | MYD88 knockdown |
| 174281 | pAPM-miR30-MYD88-ts2 | MYD88 knockdown |
| 174282 | pAPM-miR30-MYD88-ts3 | MYD88 knockdown |
| 174283 | pAPM-miR30-TMEM173-ts1 | TMEM173 knockdown |
| 174284 | pAPM-miR30-TMEM173-ts2 | TMEM173 knockdown |
| 174285 | pAPM-miR30-TMEM173-ts3 | TMEM173 knockdown |
| 174286 | pAPM-miR30-XPO1-ts1 | XPO1 knockdown |
| 174287 | pAPM-miR30-XPO1-ts2 | XPO1 knockdown |
| 174288 | pAPM-miR30-XPO1-ts3 | XPO1 knockdown |
| 174289 | pAPM-miR30-ZC3HAV1-ts1 | ZC3HAV1 knockdown |
| 174290 | pAPM-miR30-ZC3HAV1-ts2 | ZC3HAV1 knockdown |
| 174291 | pAPM-miR30-ZC3HAV1-ts3 | ZC3HAV1 knockdown |