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The ABL-MYC axis controls WIPI1-enhanced autophagy in lifespan extension.

Sporbeck K, Haas ML, Pastor-Maldonado CJ, Schussele DS, Hunter C, Takacs Z, Diogo de Oliveira AL, Franz-Wachtel M, Charsou C, Pfisterer SG, Gubas A, Haller PK, Knorr RL, Kaulich M, Macek B, Eskelinen EL, Simonsen A, Proikas-Cezanne T
Commun Biol. 2023 Aug 24;6(1):872. doi: 10.1038/s42003-023-05236-9. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
206840pGL4.23-WIPI1promotorThe plasmid contains the human WIPI1 promotor sequence (-1226 bp upstream to +329 bp downstream of the transcription start site) cloned into pGL4.23[luc2/minP] (NheI/HindIII).
206841pGL4.23-5xE-boxThe plasmid contains a 312 bp DNA fragment that contained 5 canonical E-boxes (GCCACGTGCA) spaced by 50 nucleotides and cloned into pGL4.23[luc2/minP] (XhoI/HindIII).

Antibodies from Article