Lysosomal TBK1 Responds to Amino Acid Availability to Relieve Rab7-Dependent mTORC1 Inhibition.
Talaia G, Bentley-DeSousa A, Ferguson SM
bioRxiv [Preprint]. 2023 Dec 17:2023.12.16.571979. doi: 10.1101/2023.12.16.571979.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 221550 | pSpCas9-2A-Puro-TBK1-gRNA (PX459) | Expresses Cas9 and gRNA for disruption of TBK1 gene in human cells |
| 221551 | pSpCas9-2A-Puro-RAB7A-gRNA1 (PX459) | Expresses Cas9 and gRNA for disruption of Rab7A gene in human cells |
| 221552 | pSpCas9-2A-Puro-RAB7A-gRNA2 (PX459) | Expresses Cas9 and gRNA for disruption of Rab7A gene in human cells |
| 221553 | pPB-EF1A-Puro-hTBK1-EGFP | Expresses GFP-tagged human TBK1 in mammalian cells. Compatible with piggybac transposase for genome integration. |
| 221554 | pPB-EF1A-Puro-hTBK1-E696K-EGFP | Expresses GFP-tagged human TBK1 with E696K mutation in mammalian cells. Compatible with piggybac transposase for genome integration. |
| 221555 | pPB-EF1A-Puro-mCherry-RAB7 | Expresse Cherry-tagged human Rab7 in mammalian cells. Compatible with piggybac transposase for genome integration. |
| 221556 | pPB-EF1A-Puro-mCherry-RAB7-S72A | Expresses Cherry-tagged human Rab7 with S72A mutation in mammalian cells. Compatible with piggybac transposase for genome integration. |